ISSN: 2148-8274 / E-ISSN: 2587-0084
, Türk Üreme Tıbbı ve Cerrahisi
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Turkish Journal of Reproductive Medicine and Surgery

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Açıklanamayan İnfertil Hastaların IUI Sikluslarında hCG Günü Önerilen Koitusun Gebelik Oranına Etkisi
Evaluation of Pregnancy Rate in IUI Cycles of Unexplained Infertile Patients for whom hCG Day Coitus is Recommended
Received Date : 14 Jan 2024
Accepted Date : 06 Mar 2024
Available Online : 02 Apr 2024
Doi: 10.24074/tjrms.2024-101439 - Makale Dili: EN
Turkish Journal of Reproductive Medicine and Surgery. 2024;8(2):63-8.
ÖZET
Amaç: Bu çalışmanın amacı, erkek subfertilitesi olan açıklanamayan infertil hastaların IUI sikluslarında hCG gününde önerilen koitusun intrauterin sperm sayısını artırarak gebelik ve canlı doğum oranlarını etkileyip etkilemediğini araştırmaktır. Gereç ve Yöntemler: Ali Kemal Belviranlı Kadın Doğum ve Çocuk Hastanesi İnfertilite Kliniği dosyalarından 2018-2020 yılları arasında 300 hasta verisi retrospektif olarak toplandı. 18-35 yaş grubunda açıklanamayan infertilitesi olan, antral folikül sayısı normal sınırlarda olan, FSH değeri <10 U/L ve HSG ile kanıtlanmış tüp açıklığı olan hastalar çalışmaya dahil edildi. Erkek partnerlerde total hareketli sperm sayısının (TMS) 5X106 ile 15X106 arasında olması erkek subfertilitesi olarak kabul edildi. Tüm hastalara IUI öncesinde gonadotropinler uygulandı. Katılımcıların koitus durumu ile gebelik sonuçları arasındaki ilişkiyi belirlemek için ki-kare bağımsızlık testi yapıldı. Bulgular: Retrospektif olarak incelenen hasta dosyalarından 297 hastanın 152'sine sadece IUI önerilirken, 145'ine IUI ’ a ek olarak hCG gününde koitus önerildiği tespit edildi. Doğumla sonuçlanan 29 gebelikten 8 hastaya IUI ile birlikte hCG yapıldığı gün koitus uygulandığı ve 21 hastaya sadece IUI uygulandığı tespit edildi. Erkek subfertilite hastalarında IUI'ye ek olarak hCG tetik gününde önerilen cinsel birleşmenin canlı doğum oranlarını iyileştirmediği (p>0,05) belirlendi. Sonuç: İnseminasyonla birlikte koitus önerilmesi geleneksel bir öneri olmasına rağmen, erkek subfertilitesi olan açıklanamaya infertil hastaların gonadotropinlerle indüklenmiş IUI sikluslarında Hcg günüde önerilen koitusun canlı doğum sonuçlarını iyileştirmediği sonucuna vardık.
ABSTRACT
Objective: Aim of this study is to investigate whether the recommended coitus on the day of hCG affects pregnancy and live birth rates by increasing intrauterine sperm count in IUI cycles of unexplained infertile patients with male subfertility. Material and Methods: 300 patients data is collected retrospectively from the files of the Ali Kemal Belviranlı Maternity and Children's Hospital İnfertility Clinic between 2018 and 2020. Patients with unexplained infertility in the 18-35 age group whose antral follicle count were within normal limits, FSH value <10 U/L and proven tubal patency by HSG were included in the study. In male partners, total motile sperm count (TMS) between 5X106 and 15X106 were considered as male subfertility. All patients were induced with gonadotropins before IUI. Chi-square test of independence were conducted to determine the relationship between the coitus status of the participants and pregnancy outcomes. Results: We have seen from the retrospectively reviewed patient files that while 152 of 297 patients were recommended only IUI, 145 of them were offered coitus on the day of hCG. 8 patients with 29 pregnancies that resulted in delivery applied coit on the day of hCG together with IUI and 21 patients did not apply coitus on hCG day. It was determined that recommended coitus on hCG trigger day in adition to IUI does not improve live birth rates (p>0,05) with male subfertility patients. Conclusion: Although it is a conventional recommendation to suggest coitus with insemination, we concluded that coitus does not improve pregnancy outcomes with male subfertility.
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